1,662 research outputs found

    Computing Equilibria of Semi-algebraic Economies Using Triangular Decomposition and Real Solution Classification

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    In this paper, we are concerned with the problem of determining the existence of multiple equilibria in economic models. We propose a general and complete approach for identifying multiplicities of equilibria in semi-algebraic economies, which may be expressed as semi-algebraic systems. The approach is based on triangular decomposition and real solution classification, two powerful tools of algebraic computation. Its effectiveness is illustrated by two examples of application.Comment: 24 pages, 5 figure

    Closed-Loop Brain-Computer Interfaces for Memory Restoration Using Deep Brain Stimulation

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    The past two decades have witnessed the rapid growth of therapeutic brain-computer interfaces (BCI) targeting a diversity of brain dysfunctions. Among many neurosurgical procedures, deep brain stimulation (DBS) with neuromodulation technique has emerged as a fruitful treatment for neurodegenerative disorders such as epilepsy, Parkinson\u27s disease, post-traumatic amnesia, and Alzheimer\u27s disease, as well as neuropsychiatric disorders such as depression, obsessive-compulsive disorder, and schizophrenia. In parallel to the open-loop neuromodulation strategies for neuromotor disorders, recent investigations have demonstrated the superior performance of closed-loop neuromodulation systems for memory-relevant disorders due to the more sophisticated underlying brain circuitry during cognitive processes. Our efforts are focused on discovering unique neurophysiological patterns associated with episodic memories then applying control theoretical principles to achieve closed-loop neuromodulation of such memory-relevant oscillatory activity, especially, theta and gamma oscillations. First, we use a unique dataset with intracranial electrodes inserted simultaneously into the hippocampus and seven cortical regions across 40 human subjects to test for the presence of a pattern that the phase of hippocampal theta oscillation modulates gamma oscillations in the cortex, termed cross-regional phase-amplitude coupling (xPAC), representing a key neurophysiological mechanism that promotes the temporal organization of interregional oscillatory activities, which has not previously been observed in human subjects. We then establish that the magnitude of xPAC predicts memory encoding success along with other properties of xPAC. We find that strong functional xPAC occurs principally between the hippocampus and other mesial temporal structures, namely entorhinal and parahippocampal cortices, and that xPAC is overall stronger for posterior hippocampal connections. Next, we focus on hippocampal gamma power as a `biomarker\u27 and use a novel dataset in which open-loop DBS was applied to the posterior cingulate cortex (PCC) during the encoding of episodic memories. We evaluate the feasibility of modulating hippocampal power by a precise control of stimulation via a linear quadratic integral (LQI) controller based on autoregressive with exogenous input (ARX) modeling for in-vivo use. In the simulation framework, we demonstrate proposed BCI system achieves effective control of hippocampal gamma power in 15 out of 17 human subjects and we show our DBS pattern is physiologically safe with realistic time scales. Last, we further develop the PCC-applied binary-noise (BN) DBS paradigm targeting the neuromodulation of both hippocampal theta and gamma oscillatory power in 12 human subjects. We utilize a novel nonlinear autoregressive with exogenous input neural network (NARXNN) as the plant paired with a proportional–integral–derivative (PID) controller (NARXNN-PID) for delivering a precise stimulation pattern to achieve desired oscillatory power level. Compared to a benchmark consisted of a linear state-space model (LSSM) with a PID controller, we not only demonstrate that the superior performance of our NARXNN plant model but also show the greater capacity of NARXNN-PID architecture in controlling both hippocampal theta and gamma power. We outline further experimentation to test our BCI system and compare our findings to emerging closed-loop neuromodulation strategies

    Assistance strategies for the information disadvantaged in the context of smart tourism—A study based on Dalian Tiger Beach scenic area

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    It is pointed out that with the progress of social development and science and technology, people have entered the era of mass tourism. Tourism industry relies on information more and more, but there are still some groups who cannot obtain tourism information in time, cannot share the fruits of information society, and become information disadvantaged, which affects their own development and even the harmonious development of society. Taking the elderly tourist group in Dalian Tiger Beach Scenic Area as an example, we explored the tourism market assistance strategy for the elderly tourists group in the context of intelligent tourism by using literature analysis, SWOT posture analysis and questionnaire survey. The results of the study show that the elderly have low curiosity, distrust and operational barriers in the access to information, the operation of smart tourism devices and the application of tourism app. For this reason, it is proposed that the development and promotion of smart tourism should be strongly supported at the government level; at the level of scenic spots themselves, they should scientifically and rationally design tourism routes and use unique tourism resources to build a big data platform for senior tourism information to attract tourists; at the level of smart tourism APP design, application and security, they should strive for continuous improvement and active promotion to increase user experience and trust; at the level of information disadvantaged groups themselves At the level of improvement, they should actively accept and learn new things, improve their learning enthusiasm and keep pace with the times.

    Three-dimensional ZnO hierarchical nanostructures: Solution phase synthesis and applications

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    Zinc oxide (ZnO) nanostructures have been studied extensively in the past 20 years due to their novel electronic, photonic, mechanical and electrochemical properties. Recently, more attention has been paid to assemble nanoscale building blocks into three-dimensional (3D) complex hierarchical structures, which not only inherit the excellent properties of the single building blocks but also provide potential applications in the bottom-up fabrication of functional devices. This review article focuses on 3D ZnO hierarchical nanostructures, and summarizes major advances in the solution phase synthesis, applications in environment, and electrical/electrochemical devices. We present the principles and growth mechanisms of ZnO nanostructures via different solution methods, with an emphasis on rational control of the morphology and assembly. We then discuss the applications of 3D ZnO hierarchical nanostructures in photocatalysis, field emission, electrochemical sensor, and lithium ion batteries. Throughout the discussion, the relationship between the device performance and the microstructures of 3D ZnO hierarchical nanostructures will be highlighted. This review concludes with a personal perspective on the current challenges and future research
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